Publications

Palikuqi, B.*, Rispal, J.*, Reyes, E., Vaka., D., Boffelli, D., Klein, O.^ (2022)

Lymphangiocrine factors are required for proper intestinal recovery after cytotoxic injury

Cell Stem Cell doi:10.1016/j.stem.2022.07.007; PMCID: PMC9387209  ()

The intestinal epithelium undergoes continuous renewal and has an exceptional capacity to regenerate after injury. Maintenance and proliferation of in…

Palikuqi, B., Nguyen, D., Li, G., Schreiner, R., Pellegata, A., Liu, Y., Redmond, D., Geng, F., Lin, Y., Gomez-Salinero, J., Yokoyama, M., Zumbo, P., Zhang, T., Kunar, B., Whitherspoon, M., Han, T., Tedeschi, A., Scottoni, F., Lipkin, S., Dow, L., Elemento, O., Xiang, J., Shido, K., Spence, J., Zhou, J., Schwartz, R., DeCoppi, P., Rabbany, S., Rafii, S.^ (2020)

Adaptable haemodynamic endothelial cells for organogenesis and tumorigenesis

 Nature doi:10.1038/s41586-020-2712-z; PMCID: PMC7480005

The transient reactivation of ETV2 in adult human endothelial cells reprograms these cells to become adaptable vasculogenic endothelia that in three-dimensional matrices self-assemble into vascular networks that can transport blood and physiologically arborize organoids and decellularized tissues.

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Palikuqi, B.*, Rispal, J.*, Klein, O., (2021)

Good neighbors: The niche that fine tunes mammalian intestinal regeneration

Cold Spring Harbor Perspectives in Biology doi:10.1101/cshperspect.a040865; PMCID: PMC9159262

A new type of review journal, featuring comprehensive collections of expert review articles on important topics in the molecular life sciences

Rafii, S., Palikuqi, B. (2018)

Isolation and characterization of mouse organ-specific endothelial transcriptomes

Lymphangiogenesis doi:10.1007/978-1-4939-8712-2_20; PMID: 30242768

Endothelial cells play an essential role in homeostasis and regeneration and their transcriptional profile has been found to be tissue specific. Here we describe the isolation of organ specific mouse endothelial cells using either magnetic beads or…

Zwick, R., Kasparek, P.*, Palikuqi, B.*, Viragova, S.*, Weichselbaum, L.*, McGinnis, C.*, McKinley, K., Rathnayake, A., Vaka, D.,   Nguyen, V., Trentesaux, C., Reyes, E., Gupta, A., Gartner, Z., Locksley, R., Gardner, J., Itzkovitz, S., Boffelli, D., Klein, O.* (2024)

Epithelial zonation along the mouse and human small intestine defines five discrete metabolic domains

 Nature Cell Biology doi:10.1038/s41556-023-01337-z

ZReyes, E.*, Castillo-Azofeifa, D.*, Rispal, J.*, Wald, T., Zwick, R., Palikuqi, B., Mujukian, A., Rabizadeh, S., Gupta, A., Gardner, J., Boffelli, D., Gartner, Z.*, Klein, O.*^ (2023)

Epithelial TNF controls cell differentiation and CFTR activity to maintain intestinal mucin homeostasis 

Journal of Clinical Investigation doi:10.1172/JCI163591; PMID: 37643009

Childs, C., Holloway, E., Sweet, C., Tsai, Y., Wu, A., Vallie, A., Eiken, M., Capeling, M., Zwick, R., Palikuqi, B., Trentesaux, C., Wu, J., Pellón-Cardenas, O., Zhang, C., Glass, I., Loebel, C., Yu, Q., Camp, J., Sexton, J., Klein, O., Verzi, M., Spence, J. (2023)

EPIREGULIN creates a developmental niche for spatially organized human intestinal enteroids

 JCI Insight doi:10.1172/jci.insight.165566; PMCID: PMC10070114

Choudhury, A., Cady, M., Lucas, C., Najem, H., Phillips, J., Palikuqi, B., Zakimi, N., Joseph, T., Birrueta, J., Chen, W., Bush, N., Hervey-Jumper, S., Klein, O, Toedebusch, C., Horbinski, C., Magill, S., Bhaduri, A., Perry, A., Dickinson, P., Heimberger, A., Ashworth, A., Crouch, E., Raleigh, D.^ (2023)

NOTCH3 drives meningioma tumorigenesis and resistance to radiotherapy

 bioRxiv [Preprint] doi:10.1101/2023.07.10.548456

Hisata, S.*, Racanelli, A.*^, Kermani, P., Schreiner, R., Houghton, S., Palikuqi, B., Kunar, B., Zhou, A., McConn, K., Capili, A. and Redmond, D., Nolan, D., Ginsberg, M., Ding, B., Martinez, F., Scandura, J., Cloonan, S., Rafii, S.^, Choi, A.^ (2021)

Reversal of emphysema by restoration of pulmonary endothelial cells

Journal of Experimental Medicine doi:10.1084/jem.20200938; PMCID: PMC8298104

Adelson, P., Palikuqi, B., Weiss Z., Checco, A., Schreiner, R., Rafii, S., Rabbany, S.^ (2021)

Morphological characterization of Etv2 vascular explants using fractal analysis and atomic force microscopy

Microvascular Research doi:10.1016/j.mvr.2021.104205; PMCID: PMC8446305

Merna, N., Wong, A., Barahona, V., Llanos, P., Kunar, B., Palikuqi, B., Ginsberg, M., Rafii, S., Rabbany, S.^ (2018)

Laminar shear stress modulates endothelial luminal surface stiffness in a tissue-specific manner

Microcirculation  doi:10.1111/micc.12455; PMCID: PMC6407863

Wertheimer, T.*, Velardi, E.*, Tsai, J.*, Cooper, K., Xiao, S., Kloss, C., Ottmüller, K., Mokhtari, Z., Brede, C., deRoos, P. and Kinsella, S., Palikuqi, B., Ginsberg, M., Young, L., Kreines, F., Lieberman, S., Lazrak, A., Guo, P., Malard, F., Smith, O., Shono, Y., Jenq, R., Hanash, A., Nolan, D., Butler, J., Beilhack, A., Manley, N., Rafii, S., Dudakov, J.^, van den Brink, M.^ (2018)

Production of BMP4 by endothelial cells is crucial for endogenous thymic regeneration

Science immunology  doi:10.1126/sciimmunol.aal2736; PMCID: PMC5795617

Guo, P., Poulos, M., Palikuqi, B., Badwe, C., Lis, R., Kunar, B., Ding, B., Rabbany, S., Shido, K., Butler, J., Rafii, S.^ (2017)

Endothelial jagged-2 sustains hematopoietic stem and progenitor reconstitution after myelosuppression

Journal of Clinical Investigation  doi:10.1172/JCI92309; PMCID: PMC5707154

Schachterle, W., Badwe, C., PalikuqiB., Kunar, B., Ginsberg, M., Lis, R., Yokoyama, M., Elemento, O., Scandura, J., Rafii, S.^ (2017)

Sox17 drives functional engraftment of endothelium converted from non-vascular cells

Nature Communications  doi:10.1038/ncomms13963; PMCID: PMC5260855

Nolan D., Ginsberg, M., Israely, E., Palikuqi, B., Poulos, M., James, D., Ding, B., Schachterle, W., Liu, Y., Rosenwaks, Z., Butler, J., Xiang, J., Rafii, A., Shido, K., Rabbany, S, Elemento, O., Rafii, S.^, (2013)

Molecular signatures of tissue-specific microvascular endothelial cell heterogeneity in organ maintenance and regeneration

Developmental Cell doi:10.1016/ j.devcel.2013.06. 017; PMCID: PMC3873200

Bachler, B., Humbert, M., Palikuqi, B., Siddappa, N., Lakhashe, S., Rasmussen, R., Ruprecht, R.^ (2013)

Novel biopanning strategy to identify epitopes associated with vaccine protection

Journal of Virology doi:10.1128/JVI.02888-12; PMCID: PMC3624354